GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs882367 | 1 | rs9905385 | chr17:59498250 | C17orf82 | chr17:59489112-59490641:+ | 0.19 | 4.16 | 3.93E-5 | Sitting height ratio |
| BLCA | cis | rs9910950 | 1 | rs9905408 | chr17:64190684 | AXIN2 | chr17:63524685-63637183:- | 0.52 | 4.4 | 1.41E-5 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs9905704 | 1 | rs9905704 | chr17:56632543 | SKA2 | chr17:57187308-57232800:- | 0.22 | 4.02 | 6.96E-5 | Testicular germ cell tumor |
| BLCA | cis | rs9902453 | 1 | rs9906340 | chr17:28398977 | EFCAB5 | chr17:28256874-28435469:+ | -0.23 | -4.32 | 1.97E-5 | Coffee consumption (cups per day) |
| BLCA | cis | rs9910950 | 1 | rs9908597 | chr17:64134683 | AXIN2 | chr17:63524685-63637183:- | 0.54 | 4.63 | 4.91E-6 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs7927771 | 1 | rs9909 | chr11:47799775 | C1QTNF4 | chr11:47611216-47615961:- | -0.3 | -5.65 | 3.22E-8 | Subjective well-being |
| BLCA | cis | rs9910950 | 1 | rs9910950 | chr17:64131710 | AXIN2 | chr17:63524685-63637183:- | -0.51 | -4.77 | 2.61E-6 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs9910950 | 1 | rs9911603 | chr17:64131902 | AXIN2 | chr17:63524685-63637183:- | 0.56 | 4.92 | 1.3E-6 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs7224737 | 1 | rs9912088 | chr17:40288278 | DHX58 | chr17:40253422-40264751:- | -0.25 | -4.56 | 6.82E-6 | Fibrinogen levels |
| BLCA | cis | rs9902453 | 1 | rs9912741 | chr17:28359511 | EFCAB5 | chr17:28256874-28435469:+ | -0.22 | -3.85 | 0.00014 | Coffee consumption (cups per day) |
| BLCA | cis | rs7224737 | 1 | rs9915255 | chr17:40284191 | DHX58 | chr17:40253422-40264751:- | -0.25 | -4.65 | 4.66E-6 | Fibrinogen levels |
| BLCA | cis | rs4494548 | 1 | rs9926996 | chr16:20395908 | C16orf88 | chr16:19717676-19729492:- | -0.37 | -4.01 | 7.16E-5 | Urinary uromodulin levels |
| BLCA | cis | rs10935120 | 1 | rs9968172 | chr3:134231251 | ANAPC13 | chr3:134196547-134204865:- | -0.51 | -8.22 | 3.15E-15 | Height |
| BLCA | cis | rs10935120 | 1 | rs9968172 | chr3:134231251 | CEP63 | chr3:134204575-134293852:+ | -0.28 | -4.84 | 1.86E-6 | Height |
| BLCA | cis | rs1930961 | 1 | rs997872 | chr22:25878614 | CRYBB2 | chr22:25615612-25627836:+ | 0.93 | 9.71 | 4.39E-20 | Bipolar disorder with mood-incongruent psychosis |